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The antibody against GATA2 was raised in rabbit using the Peptide sequence around phosphorylation site of Serine 401(K-M-S(p)-N-K) derived from Human GATA2 . as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
The antibody against GATA2 was raised in rabbit using the Peptide sequence around phosphorylation site of Serine 401(K-M-S(p)-N-K) derived from Human GATA2 . as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from JK cells (Lane 2), using GATA2 (Phospho-Ser401) Antibody. The lane on the left is treated with antigen-specific peptide.
| Cat.No | ADC-42772A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GATA2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around phosphorylation site of Serine 401(K-M-S(p)-N-K) derived from Human GATA2 . | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23769 |
Uniprot Id
P23769
Target Species
Human
Target Name
GATA2
Target Full Name
Endothelial transcription factor GATA-2
Target Function
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.
Target Involvement
Immunodeficiency 21 (IMD21); Lymphedema, primary, with myelodysplasia (LMPM); Myelodysplastic syndrome (MDS)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Endothelial cells.
Target Synonyms
DCML; Endothelial transcription factor GATA 2; Endothelial transcription factor GATA-2; Endothelial transcription factor GATA2; FLJ45948; GATA 2; GATA binding protein 2; GATA-binding protein 2; Gata2; GATA2_HUMAN; IMD21; MGC2306; MONOMAC; NFE 1B; NFE1B; OTTHUMP00000216240
Target Background
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
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