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The antibody against GCA was raised in rabbit using the Recombinant Human Grancalcin protein (1-217AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GCA was raised in rabbit using the Recombinant Human Grancalcin protein (1-217AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human tonsil tissue using GCA Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using GCA Antibody at dilution of 1:1002
| Cat.No | ADC-17527A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GCA |
| Target Synonyms | GCA antibody; GCL antibody; Grancalcin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Grancalcin protein (1-217AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P28676 |
Uniprot Id
P28676
Target Species
Human
Target Name
GCA
Target Full Name
Grancalcin
Target Function
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Target Subcellular Location
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Target Research Area
others
Target Synonyms
GCA; GCL; Grancalcin
Target Background
This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants.
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