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The antibody against GCGR was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Glucagon Receptor. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against GCGR was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Glucagon Receptor. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
$167.00
Western Blot analysis of COLO205 cells using Glucagon Receptor Polyclonal Antibody
Western Blot analysis of COLO205 cells using Glucagon Receptor Polyclonal Antibody2
| Cat.No | ADC-38587A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GCGR |
| Target Synonyms | GCGR; Glucagon receptor; GL-R | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Glucagon Receptor. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P47871 |
Uniprot Id
P47871
Target Species
Human
Target Name
GCGR
Target Full Name
Glucagon receptor
Target Function
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Research Area
Cancer
Target Synonyms
GCGR; Glucagon receptor; GL-R
Target Background
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
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