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Rabbit anti-Human GEM Polyclonal Antibody

The antibody against GEM was raised in rabbit using the Human GEM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48475A

The antibody against GEM was raised in rabbit using the Human GEM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-48475A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGEM
Target SynonymsGEM antibody; KIRGTP-binding protein GEM antibody; GTP-binding mitogen-induced T-cell protein antibody; RAS-like protein KIR antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman GEMTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP55040
Background Information
  • Uniprot Id

    P55040

  • Target Species

    Human

  • Target Name

    GEM

  • Target Full Name

    GTP-binding protein GEM

  • Target Function

    Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    Small GTPase superfamily, RGK family

  • Target Tissue Specificity

    Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.

  • Target Synonyms

    GEM; KIRGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR

  • Target Background

    The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

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