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Rabbit anti-Human GFRA4 Polyclonal Antibody

The antibody against GFRA4 was raised in rabbit using the Synthetic peptide of Human GFRA4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-27946A

The antibody against GFRA4 was raised in rabbit using the Synthetic peptide of Human GFRA4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-27946A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGFRA4
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human GFRA4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9GZZ7
Background Information
  • Uniprot Id

    Q9GZZ7

  • Target Species

    Human

  • Target Name

    GFRA4

  • Target Full Name

    GDNF family receptor alpha-4

  • Target Function

    Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.

  • Target Subcellular Location

    [Isoform GFRalpha4a]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4b]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4c]: Secreted.

  • Target Protein Families

    GDNFR family

  • Target Tissue Specificity

    Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands.

  • Target Synonyms

    GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha 4; GFR receptor alpha 4; GFR-alpha-4; GFRA4; GFRA4_HUMAN; Glial cell line derived neurotrophic factor family receptor alpha 4; Neurotrophic factor receptor splice variant A (Gfra4 gene); OTTHUMP00000030106; OTTHUMP00000030107; Persephin receptor

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