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The antibody against GGH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GGH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03775A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GGH |
| Target Synonyms | GH; GATD10; GGH | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q92820 | Immunogen Sequence |
Uniprot Id
Q92820
Target Species
Human
Target Name
GGH
Target Full Name
Gamma-glutamyl hydrolase
Target Function
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Target Subcellular Location
Secreted, extracellular space. Lysosome. Melanosome.
Target Protein Families
Peptidase C26 family
Target Synonyms
Conjugase; folylpolygammaglutamyl hydrolase; gamma glutamyl hydrolase; Gamma-Glu-X carboxypeptidase; Gamma-glutamyl hydrolase (conjugase; folylpolygammaglutamyl hydrolase); Gamma-glutamyl hydrolase; GGH; GGH_HUMAN; gH
Target Background
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.
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