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The antibody against GHRHR was raised in rabbit using the Recombinant Human Growth hormone-releasing hormone receptor protein (23-127AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against GHRHR was raised in rabbit using the Recombinant Human Growth hormone-releasing hormone receptor protein (23-127AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-06925A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GHRHR |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Growth hormone-releasing hormone receptor protein (23-127AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q02643 |
Uniprot Id
Q02643
Target Species
Human
Target Name
GHRHR
Target Full Name
Growth hormone-releasing hormone receptor
Target Function
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Target Involvement
Growth hormone deficiency, isolated, 1B (IGHD1B)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Pituitary gland.
Target Synonyms
GRFR; GHRFR; IGHD4; IGHD1B; GHRHR
Target Background
This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.
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