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Rabbit anti-Human GLO1 Monoclonal Antibody

The antibody against GLO1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLO1 (Q04760) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13847A

The antibody against GLO1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLO1 (Q04760) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13847A ClonalityMonoclonal
Host SpeciesRabbitTarget NameGLO1
Target SynonymsGLYI; GLOD1; HEL-S-74; GLO1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Rat brain, HT-29, Mouse brain, Rat lungApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human GLO1 (Q04760).Target SpeciesHuman
Immunogen SequenceMAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLEUniprot IDQ04760
Background Information
  • Uniprot Id

    Q04760

  • Target Species

    Human

  • Target Name

    GLO1

  • Target Full Name

    Lactoylglutathione lyase

  • Target Function

    Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.

  • Target Protein Families

    Glyoxalase I family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Aldoketomutase; glo1; GLOD1; Glx I; GLYI; glyoxalase domain containing 1; Glyoxalase I; Ketone aldehyde mutase ; Ketone-aldehyde mutase; Lactoyl glutathione lyase ; Lactoylglutathione lyase; LGUL_HUMAN; Methylglyoxalase; S D lactoylglutathione methylglyoxal lyase ; S-D-lactoylglutathione methylglyoxal lyase

  • Target Background

    The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.

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