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Rabbit anti-Human GNL2 Polyclonal Antibody

The antibody against GNL2 was raised in rabbit using the Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-44810A

The antibody against GNL2 was raised in rabbit using the Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-44810A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGNL2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ13823
Background Information
  • Uniprot Id

    Q13823

  • Target Species

    Human

  • Target Name

    GNL2

  • Target Full Name

    Nucleolar GTP-binding protein 2

  • Target Function

    GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Protein Families

    TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily

  • Target Tissue Specificity

    Widely expressed, with the highest expression level in testis.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    Autoantigen NGP-1; Autoantigen NGP1; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein; FLJ40906; GNL2; Guanine nucleotide binding protein-like 2 (nucleolar); HUMAUANTIG; NGP1; NOG2_HUMAN; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP binding protein 2; Nucleolar GTP-binding protein 2; Nucleolar GTPase

  • Target Background

    Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus.

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