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The antibody against GNL2 was raised in rabbit using the Human GNL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GNL2 was raised in rabbit using the Human GNL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-53231A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GNL2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Human GNL2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13823 |
Uniprot Id
Q13823
Target Species
Human
Target Name
GNL2
Target Full Name
Nucleolar GTP-binding protein 2
Target Function
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
Target Tissue Specificity
Widely expressed, with the highest expression level in testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Autoantigen NGP-1; Autoantigen NGP1; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein; FLJ40906; GNL2; Guanine nucleotide binding protein-like 2 (nucleolar); HUMAUANTIG; NGP1; NOG2_HUMAN; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP binding protein 2; Nucleolar GTP-binding protein 2; Nucleolar GTPase
Target Background
Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus.
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