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The antibody against GOSR1 was raised in rabbit using the Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GOSR1 was raised in rabbit using the Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using GOSR1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using GOSR1 Antibody at dilution of 1:1002
| Cat.No | ADC-40045A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GOSR1 |
| Target Synonyms | GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95249 |
Uniprot Id
O95249
Target Species
Human
Target Name
GOSR1
Target Full Name
Golgi SNAP receptor complex member 1
Target Function
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type IV membrane protein.
Target Protein Families
GOSR1 family
Target Synonyms
GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
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