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The antibody against GPA33 was raised in rabbit using the Recombinant Human Cell surface A33 antigen protein (22-235AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against GPA33 was raised in rabbit using the Recombinant Human Cell surface A33 antigen protein (22-235AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-32802A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPA33 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cell surface A33 antigen protein (22-235AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99795 |
Uniprot Id
Q99795
Target Species
Human
Target Name
GPA33
Target Full Name
Cell surface A33 antigen
Target Function
May play a role in cell-cell recognition and signaling.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
Target Synonyms
A33; Cell surface A33 antigen; Cell surface A33 antigen precursor; Glycoprotein A33 (transmembrane); Glycoprotein A33; Gpa33; GPA33_HUMAN; MGC129986; MGC129987; OTTHUMP00000032346; Transmembrane glycoprotein A33
Target Background
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
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