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The antibody against GPAA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-310 of human GPAA1 (NP_003792.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GPAA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-310 of human GPAA1 (NP_003792.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05987A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPAA1 |
| Target Synonyms | GAA1; hGAA1; GPIBD15; GPAA1 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 90-310 of human GPAA1 (NP_003792.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43292 | Immunogen Sequence |
Uniprot Id
O43292
Target Species
Human
Target Name
GPAA1
Target Full Name
Glycosylphosphatidylinositol anchor attachment 1 protein
Target Function
Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Tissue Specificity
Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues.
Target Synonyms
GPAA1; GAA1; Glycosylphosphatidylinositol anchor attachment 1 protein; GPI anchor attachment protein 1; GAA1 protein homolog; hGAA1
Target Background
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.
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