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The antibody against GPD1 was raised in rabbit using the Recombinant Human Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic protein (1-349AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against GPD1 was raised in rabbit using the Recombinant Human Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic protein (1-349AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human breast cancer using GPD1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using GPD1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-45739A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPD1 |
| Target Synonyms | cytoplasmic antibody; Glycerol-3-phosphate dehydrogenase 1 (soluble) antibody; Glycerol-3-phosphate dehydrogenase antibody; Glycerol-3-phosphate dehydrogenase | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic protein (1-349AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P21695 |
Uniprot Id
P21695
Target Species
Human
Target Name
GPD1
Target Full Name
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Target Function
Has glycerol-3-phosphate dehydrogenase activity.
Target Involvement
Hypertriglyceridemia, transient infantile (HTGTI)
Target Subcellular Location
Cytoplasm.
Target Protein Families
NAD-dependent glycerol-3-phosphate dehydrogenase family
Target Tissue Specificity
Expressed in liver (at protein level).
Target Research Area
Signal Transduction
Target Synonyms
AI747587; cytoplasmic; EC 1.1.1.8; FLJ26652; G3PD; Gdc-1; Gdc1; Gdp1; Glycerol 3 phosphate dehydrogenase 1; Glycerol 3 phosphate dehydrogenase cytosolic; Glycerol 3 phosphate dehydrogenase soluble; Glycerol-3-phosphate dehydrogenase [NAD+]; Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; Glycerol-3-phosphate dehydrogenase 1 (soluble); Glycerol-3-phosphate dehydrogenase; Glycerol-3-phosphate dehydrogenase, soluble ; Glycerphosphate dehydrogenase; GPD-C; gpd1; Gpd1 protein; Gpd3; GPDA_HUMAN; Gpdc; GPDH; GPDH-C; Gpdhc; HTGTI; KIAA4010; MGC93453; MGPD; mKIAA4010
Target Background
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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