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The antibody against GPR126 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GPR126 (NP_001027567.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GPR126 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GPR126 (NP_001027567.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01415A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPR126 |
| Target Synonyms | APG1; DREG; VIGR; LCCS9; PR126; GPR126; PS1TP2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human GPR126 (NP_001027567.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q86SQ4 | Immunogen Sequence |
Uniprot Id
Q86SQ4
Target Species
Human
Target Name
ADGRG6
Target Full Name
Adhesion G-protein coupled receptor G6
Target Function
G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis.
Target Involvement
Lethal congenital contracture syndrome 9 (LCCS9)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity
Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
Target Research Area
Others
Target Synonyms
adhesion G protein coupled receptor G6; APG1; Developmentally regulated G protein coupled receptor; Developmentally regulated G-protein-coupled receptor; dj287g14.2; DREG; G protein coupled receptor 126; G-protein coupled receptor 126; GP126_HUMAN; GPR126; HBV PreS1 transactivated protein 2; HBV PreS1-transactivated protein 2; LCCS9; OTTHUMP00000017320; OTTHUMP00000237093; OTTHUMP00000237094; OTTHUMP00000237115; PR126; Probable G protein coupled receptor 126 [Precursor]; Probable G protein coupled receptor 126; Probable G-protein coupled receptor 126 [Precursor]; Probable G-protein coupled receptor 126; PS1TP2; Vascular inducible G protein coupled receptor; Vascular inducible G protein-coupled receptor; VIGR
Target Background
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene.
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