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Rabbit anti-Human GPR132 Polyclonal Antibody

The antibody against GPR132 was raised in rabbit using the Human GPR132 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-48425A

The antibody against GPR132 was raised in rabbit using the Human GPR132 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$600.00

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Specifications


Cat.No ADC-48425A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGPR132
Target SynonymsGPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation proteinFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman GPR132Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UNW8
Background Information
  • Uniprot Id

    Q9UNW8

  • Target Species

    Human

  • Target Name

    GPR132

  • Target Full Name

    Probable G-protein coupled receptor 132

  • Target Function

    May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.

  • Target Synonyms

    GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein

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