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Rabbit anti-Human GPR139 Polyclonal Antibody

The antibody against GPR139 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-353 of human GPR139 (Q6DWJ6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04724A

The antibody against GPR139 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-353 of human GPR139 (Q6DWJ6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04724A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGPR139
Target SynonymsPGR3; GPRg1; GPR139FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 290-353 of human GPR139 (Q6DWJ6).Target SpeciesHuman
Immunogen SequenceKRFRTMAAATLKAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSPUniprot IDQ6DWJ6
Background Information
  • Uniprot Id

    Q6DWJ6

  • Target Species

    Human

  • Target Name

    GPR139

  • Target Full Name

    Probable G-protein coupled receptor 139

  • Target Function

    Orphan receptor. Seems to act through a G(q/11)-mediated pathway.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.

  • Target Synonyms

    GPR139; GPRG1; PGR3; Probable G-protein coupled receptor 139; G(q-coupled orphan receptor GPRg1; G-protein-coupled receptor PGR3

  • Target Background

    This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.

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