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Rabbit anti-Human GPR153 Polyclonal Antibody

The antibody against GPR153 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GPR153. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-35226A

The antibody against GPR153 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GPR153. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-35226A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGPR153
Target SynonymsGPR153; PGR1; Probable G-protein coupled receptor 153; G-protein coupled receptor PGR1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human GPR153.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6NV75
Background Information
  • Uniprot Id

    Q6NV75

  • Target Species

    Human

  • Target Name

    GPR153

  • Target Full Name

    Probable G-protein coupled receptor 153

  • Target Function

    Orphan receptor.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Synonyms

    GPR153; PGR1; Probable G-protein coupled receptor 153; G-protein coupled receptor PGR1

  • Target Background

    This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.

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