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The antibody against GPRASP1 was raised in rabbit using the Human GPRASP1-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GPRASP1 was raised in rabbit using the Human GPRASP1-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-46589A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPRASP1 |
| Target Synonyms | G-protein coupled receptor-associated sorting protein 1 antibody; GASP antibody; GASP-1 antibody; GASP1 antibody; GASP1_HUMAN antibody; Gprasp1 antibody; KIAA0443 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Human GPRASP1-Specific | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5JY77 |
Uniprot Id
Q5JY77
Target Species
Human
Target Name
GPRASP1
Target Full Name
G-protein coupled receptor-associated sorting protein 1
Target Function
Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
Target Subcellular Location
Cytoplasm.
Target Protein Families
GPRASP family
Target Tissue Specificity
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
Target Synonyms
G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; GASP1_HUMAN; Gprasp1; KIAA0443
Target Background
This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.
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