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The antibody against GRIK1 was raised in rabbit using the Recombinant Human Glutamate receptor ionotropic, kainate 1 protein (675-834AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against GRIK1 was raised in rabbit using the Recombinant Human Glutamate receptor ionotropic, kainate 1 protein (675-834AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human thyroid tissue using GRIK1 Antibody at dilution of 1:100
| Cat.No | ADC-08551A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIK1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Glutamate receptor ionotropic, kainate 1 protein (675-834AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P39086 |
Uniprot Id
P39086
Target Species
Human
Target Name
GRIK1
Target Full Name
Glutamate receptor ionotropic, kainate 1
Target Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, GRIK1 subfamily
Target Tissue Specificity
Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Target Synonyms
EAA3; EEA3; Excitatory amino acid receptor 3; GLR5; GluR-5; GluR5; GluR6; GluR7; Glutamate receptor 5; Glutamate receptor; Glutamate receptor ionotropic kainate 1; GRIK1; GRIK1_HUMAN; Human glutamate receptor GLUR5; ionotropic kainate 1; OTTHUMP00000096569
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