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The antibody against GRIK1 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human GluR-5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against GRIK1 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human GluR-5. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-35503A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIK1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human GluR-5. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P39086 |
Uniprot Id
P39086
Target Species
Human
Target Name
GRIK1
Target Full Name
Glutamate receptor ionotropic, kainate 1
Target Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, GRIK1 subfamily
Target Tissue Specificity
Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Target Synonyms
EAA3; EEA3; Excitatory amino acid receptor 3; GLR5; GluR-5; GluR5; GluR6; GluR7; Glutamate receptor 5; Glutamate receptor; Glutamate receptor ionotropic kainate 1; GRIK1; GRIK1_HUMAN; Human glutamate receptor GLUR5; ionotropic kainate 1; OTTHUMP00000096569
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