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The antibody against GRIK1 was raised in rabbit using the Synthesized peptide derived from Human GluR5. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against GRIK1 was raised in rabbit using the Synthesized peptide derived from Human GluR5. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR5 antibody.
Western blot analysis of extracts from mouse brain, using GluR5 antibody.2
Western blot analysis of extracts from HepG2 cells (Lane 2), using GluR5 antiobdy. The lane on the left is treated with synthesized peptide.3
| Cat.No | ADC-42401A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIK1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human GluR5. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P39086 |
Uniprot Id
P39086
Target Species
Human
Target Name
GRIK1
Target Full Name
Glutamate receptor ionotropic, kainate 1
Target Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, GRIK1 subfamily
Target Tissue Specificity
Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Target Synonyms
EAA3; EEA3; Excitatory amino acid receptor 3; GLR5; GluR-5; GluR5; GluR6; GluR7; Glutamate receptor 5; Glutamate receptor; Glutamate receptor ionotropic kainate 1; GRIK1; GRIK1_HUMAN; Human glutamate receptor GLUR5; ionotropic kainate 1; OTTHUMP00000096569
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