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The antibody against GRIP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GRIP1 (NP_001171545.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GRIP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GRIP1 (NP_001171545.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03686A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIP1 |
| Target Synonyms | GRIP; FRASRS3; GRIP1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GRIP1 (NP_001171545.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y3R0 | Immunogen Sequence |
Uniprot Id
Q9Y3R0
Target Species
Human
Target Name
GRIP1
Target Full Name
Glutamate receptor-interacting protein 1
Target Function
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
Target Involvement
Fraser syndrome 3 (FRASRS3)
Target Subcellular Location
Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cytoplasm. Endomembrane system; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic density. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Synonyms
as GRIP; Glutamate receptor-interacting protein 1; GRIP-1; Grip1; GRIP1_HUMAN
Target Background
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
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