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The antibody against GRPEL2 was raised in rabbit using the Recombinant Human GrpE protein homolog 2, mitochondrial protein (33-225AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against GRPEL2 was raised in rabbit using the Recombinant Human GrpE protein homolog 2, mitochondrial protein (33-225AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using GRPEL2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using GRPEL2 Antibody at dilution of 1:1002
| Cat.No | ADC-16251A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRPEL2 |
| Target Synonyms | GrpE like 2; mitochondrial antibody; GrpE protein homolog 2 antibody; GRPE2_HUMAN antibody; GRPEL 2 antibody; Grpel2 antibody; mitochondrial antibody; Mt GrpE#2 antibody; Mt-GrpE#2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human GrpE protein homolog 2, mitochondrial protein (33-225AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TAA5 |
Uniprot Id
Q8TAA5
Target Species
Human
Target Name
GRPEL2
Target Full Name
GrpE protein homolog 2, mitochondrial
Target Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
GrpE family
Target Synonyms
GrpE like 2; mitochondrial; GrpE protein homolog 2; GRPE2_HUMAN; GRPEL 2; Grpel2; mitochondrial; Mt GrpE#2; Mt-GrpE#2
Target Background
Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion.
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