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Rabbit anti-Human GSC Polyclonal Antibody

The antibody against GSC was raised in rabbit using the Synthetic peptide from Human protein at AA range: 207-256 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-12973A

The antibody against GSC was raised in rabbit using the Synthetic peptide from Human protein at AA range: 207-256 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-12973A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGSC
Target SynonymsGoosecoid antibody; goosecoid homeobox antibody; GSC antibody; GSC_HUMAN antibody; Homeobox protein goosecoid antibodyFormLiquid
Species ReactivityHuman, Mouse, RatStorage BufferPH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS
Purification MethodThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide from Human protein at AA range: 207-256Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP56915
Background Information
  • Uniprot Id

    P56915

  • Target Species

    Human

  • Target Name

    GSC

  • Target Full Name

    Homeobox protein goosecoid

  • Target Function

    Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring. Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.

  • Target Involvement

    Short stature, auditory canal atresia, mandibular hypoplasia, skeletal abnormalities (SAMS)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Paired homeobox family, Bicoid subfamily

  • Target Synonyms

    Goosecoid; goosecoid homeobox; GSC; GSC_HUMAN; Homeobox protein goosecoid

  • Target Background

    This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.

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