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The antibody against GSR was raised in rabbit using the Human GSR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against GSR was raised in rabbit using the Human GSR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-53188A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GSR |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Human GSR | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00390 |
Uniprot Id
P00390
Target Species
Human
Target Name
GSR
Target Full Name
Glutathione reductase, mitochondrial
Target Function
Maintains high levels of reduced glutathione in the cytosol.
Target Subcellular Location
[Isoform Mitochondrial]: Mitochondrion.; [Isoform Cytoplasmic]: Cytoplasm.
Target Protein Families
Class-I pyridine nucleotide-disulfide oxidoreductase family
Target Synonyms
GLR1; GLUR; Glutathione reductase; Glutathione reductase mitochondrial; Glutathione reductase; mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSHR_HUMAN; GSR; MGC78522
Target Background
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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