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The antibody against GTF3C6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GTF3C6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03538A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GTF3C6 |
| Target Synonyms | C6orf51; TFIIIC35; bA397G5.3; GTF3C6 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human GTF3C6 (NP_612417.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q969F1 | Immunogen Sequence |
Uniprot Id
Q969F1
Target Species
Human
Target Name
GTF3C6
Target Full Name
General transcription factor 3C polypeptide 6
Target Function
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
Target Subcellular Location
Nucleus.
Target Protein Families
TFIIIC subunit 6 family
Target Synonyms
GTF3C6; C6orf51; CDA020; NPD020; General transcription factor 3C polypeptide 6; Transcription factor IIIC 35 kDa subunit; TFIIIC 35 kDa subunit; TFIIIC35; Transcription factor IIIC subunit 6
Target Background
RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.
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