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The antibody against GTPBP10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-387 of human GTPBP10 (NP_149098.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GTPBP10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-387 of human GTPBP10 (NP_149098.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07489A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GTPBP10 |
| Target Synonyms | ObgH2; UG0751c10; GTPBP10 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-431, A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-387 of human GTPBP10 (NP_149098.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | A4D1E9 | Immunogen Sequence |
Uniprot Id
A4D1E9
Target Species
Human
Target Name
GTPBP10
Target Full Name
GTP-binding protein 10
Target Function
May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed.
Target Subcellular Location
Nucleus, nucleolus. Chromosome. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase. Gradually re-assembles into the nucleolus at late anaphase to telophase.
Target Protein Families
TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
Target Synonyms
GTPBP10; OBGH2; UG0751c10GTP-binding protein 10; Protein obg homolog 2; ObgH2
Target Background
Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).
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