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The antibody against GUCA1A was raised in rabbit using the Human GUCA1A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against GUCA1A was raised in rabbit using the Human GUCA1A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48387A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GUCA1A |
| Target Synonyms | GUCA1A antibody; C6orf131 antibody; GCAP antibody; GCAP1 antibody; GUCA1 antibody; Guanylyl cyclase-activating protein 1 antibody; GCAP 1 antibody; Guanylate cyclase activator 1A antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human GUCA1A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P43080 |
Uniprot Id
P43080
Target Species
Human
Target Name
GUCA1A
Target Full Name
Guanylyl cyclase-activating protein 1
Target Function
Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.
Target Involvement
Cone dystrophy 3 (COD3)
Target Subcellular Location
Membrane; Lipid-anchor. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Target Tissue Specificity
In the retina, it is expressed in rod and cone photoreceptors.
Target Synonyms
GUCA1A; C6orf131; GCAP; GCAP1; GUCA1; Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A
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