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Rabbit anti-Human GULP1 Polyclonal Antibody, HRP conjugated

The antibody against GULP1 was raised in rabbit using the Recombinant Human PTB domain-containing engulfment adapter protein 1 protein (199-279AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-11547A

The antibody against GULP1 was raised in rabbit using the Recombinant Human PTB domain-containing engulfment adapter protein 1 protein (199-279AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-11547A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGULP1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateHRP conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human PTB domain-containing engulfment adapter protein 1 protein (199-279AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBP9
Background Information
  • Uniprot Id

    Q9UBP9

  • Target Species

    Human

  • Target Name

    GULP1

  • Target Full Name

    PTB domain-containing engulfment adapter protein 1

  • Target Function

    May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.

  • Target Subcellular Location

    Cytoplasm. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes.

  • Target Protein Families

    Ced-6 family

  • Target Tissue Specificity

    Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.

  • Target Synonyms

    CED6; Cell death protein 6 homolog; Engulfment adapter protein; Engulfment adaptor PTB domain containing 1; GULP; GULP; engulfment adaptor PTB domain containing 1; GULP1; GULP1_HUMAN; Protein GULP; PTB domain adapter protein CED 6; PTB domain adapter protein CED-6; PTB domain adaptor protein CED6; PTB domain-containing engulfment adapter protein 1

  • Target Background

    The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene.

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