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The antibody against GYPC was raised in rabbit using the Synthetic peptide from Human protein at AA range: 11-60 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against GYPC was raised in rabbit using the Synthetic peptide from Human protein at AA range: 11-60 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
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Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:2002
Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:2003
| Cat.No | ADC-12993A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GYPC |
| Target Synonyms | GYPC; GLPC; GPC; Glycophorin-C; Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D; CD antigen CD236 | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS |
| Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 11-60 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04921 |
Uniprot Id
P04921
Target Species
Human
Target Name
GYPC
Target Full Name
Glycophorin-C
Target Function
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
Target Subcellular Location
Cell membrane; Single-pass type III membrane protein. Note=Linked to the membrane via band 4.1.
Target Protein Families
Glycophorin-C family
Target Tissue Specificity
Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
Target Synonyms
GYPC; GLPC; GPC; Glycophorin-C; Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D; CD antigen CD236
Target Background
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
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