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Rabbit anti-Human GYS2 Polyclonal Antibody

The antibody against GYS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 594-703 of human GYS2 (NP_068776.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03376A

The antibody against GYS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 594-703 of human GYS2 (NP_068776.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03376A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGYS2
Target SynonymsGYS2FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 594-703 of human GYS2 (NP_068776.2).Target SpeciesHuman
Immunogen SequenceDLLDWRYLGRYYQHARHLTLSRAFPDKFHVELTSPPTTEGFKYPRPSSVPPSPSGSQASSPQSSDVEDEVEDERYDEEEEAERDRLNIKSPFSLSHVPHGKKKLHGEYKNUniprot IDP54840
Background Information
  • Uniprot Id

    P54840

  • Target Species

    Human

  • Target Name

    GYS2

  • Target Full Name

    Glycogen [starch] synthase, liver

  • Target Function

    Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

  • Target Involvement

    Glycogen storage disease 0 (GSD0)

  • Target Protein Families

    Glycosyltransferase 3 family

  • Target Synonyms

    EC 2.4.1.11; Glycogen [starch] synthase; Glycogen starch synthase liver; Glycogen synthase 2 liver; Gys2; GYS2_HUMAN; liver

  • Target Background

    The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.

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