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Rabbit anti-Human GZMK Polyclonal Antibody, HRP conjugated

The antibody against GZMK was raised in rabbit using the Recombinant Human Granzyme K protein (27-264AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-11098A

The antibody against GZMK was raised in rabbit using the Recombinant Human Granzyme K protein (27-264AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-11098A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGZMK
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateHRP conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Granzyme K protein (27-264AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49863
Background Information
  • Uniprot Id

    P49863

  • Target Species

    Human

  • Target Name

    GZMK

  • Target Full Name

    Granzyme K

  • Target Subcellular Location

    Secreted. Cytoplasmic granule.

  • Target Protein Families

    Peptidase S1 family, Granzyme subfamily

  • Target Tissue Specificity

    Expressed in lung, spleen, thymus and peripheral blood leukocytes.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease; granzyme 3; tryptase II); Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2; NKTRYP2; Serine protease granzyme 3; TRYP 2; TRYP2; Tryptase II; TryptaseII

  • Target Background

    This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

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