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The antibody against GZMM was raised in rabbit using the Recombinant Human Granzyme M protein (98-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against GZMM was raised in rabbit using the Recombinant Human Granzyme M protein (98-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human lung tissue using GZMM Antibody at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using GZMM Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-11095A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GZMM |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Granzyme M protein (98-243AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51124 |
Uniprot Id
P51124
Target Species
Human
Target Name
GZMM
Target Full Name
Granzyme M
Target Function
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Target Subcellular Location
Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes.
Target Protein Families
Peptidase S1 family, Granzyme subfamily
Target Tissue Specificity
Highly and constitutively expressed in activated natural killer (NK) cells.
Target Synonyms
GRAM_HUMAN; Granzyme M (lymphocyte met ase 1); Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease
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