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The antibody against GZMM was raised in rabbit using the Synthetic peptide from Human protein at AA range: 207-256 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against GZMM was raised in rabbit using the Synthetic peptide from Human protein at AA range: 207-256 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded Human-lymph, antibody was diluted at 1:1002
Immunohistochemical analysis of paraffin-embedded Human-lymph, antibody was diluted at 1:1003
| Cat.No | ADC-12945A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GZMM |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 207-256 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51124 |
Uniprot Id
P51124
Target Species
Human
Target Name
GZMM
Target Full Name
Granzyme M
Target Function
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Target Subcellular Location
Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes.
Target Protein Families
Peptidase S1 family, Granzyme subfamily
Target Tissue Specificity
Highly and constitutively expressed in activated natural killer (NK) cells.
Target Synonyms
GRAM_HUMAN; Granzyme M (lymphocyte met ase 1); Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease
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