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The antibody against H1FOO was raised in rabbit using the Synthesized peptide derived from Human Histone H1 around the non-acetylation site of K25. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.
The antibody against H1FOO was raised in rabbit using the Synthesized peptide derived from Human Histone H1 around the non-acetylation site of K25. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.
$167.00
| Cat.No | ADC-36356A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | H1FOO |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Histone H1 around the non-acetylation site of K25. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZA3 |
Uniprot Id
Q8IZA3
Target Species
Human
Target Name
H1-8
Target Full Name
Histone H1.8
Target Function
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Target Subcellular Location
Cytoplasm. Nucleus. Chromosome.
Target Protein Families
Histone H1/H5 family
Target Tissue Specificity
Oocyte-specific.
Target Synonyms
dJ221C16.2; dJ221C16.5; DmeH1; H1 0 histone ; H1; H1 histone family member 0; H1 histone family member 1; H1 histone family member 3 ; H1 histone family member 5; H1 histone family member N testis specific; H1 histone family member O oocyte specific; H1 histone family member X; H1(0); H1.1; H1.2; H1.3; H1.4; H1.5; H10; H1A; H1f0; H1F0 protein; H1F1; H1F2; H1F3; H1F4; H1F5; H1FNT; H1FOO; H1FOO protein; H1FOO_HUMAN; H1FT; H1FV; H1FX; H1oo; H1t; H1T2; H1X; HANP1; His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Histone 1 H1a; Histone 1 H1b; Histone 1 H1c; Histone 1 H1d; Histone 1 H1e; Histone 1 H1t; Histone; Histone H1' ; Histone H1.0; Histone H1.1; Histone H1.2; Histone H1.3; Histone H1.4; Histone H1.5; Histone H1oo; Histone H1x; MGC116819; MGC126630; MGC126632; MGC126642; MGC138176; MGC138345; MGC15959; MGC3992; MGC50807; MGC5241; MGC8350; Oocyte specific histone H1; Oocyte specific linker histone H1; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1; Testicular H1 histone
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