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The antibody against HAL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HAL (NP_002099.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against HAL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HAL (NP_002099.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-09571A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAL |
| Target Synonyms | HIS; HSTD; HAL | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat liver | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HAL (NP_002099.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MPRYTVHVRGEWLAVPCQDAQLTVGWLGREAVRRYIKNKPDNGGFTSVDDAHFLVRRCKGLGLLDNEDRLEVALENNEFVEVVIEGDAMSPDFIPSQPEGVYLYSKYREPEKYIELDGDRLTTEDLVNLGKGRYKIKLTPTAEKRVQKSREVIDSIIKEKTVVYGITTGFGKFARTVIPINKLQELQVNLVRSHSSGVGK | Uniprot ID | P42357 |
Uniprot Id
P42357
Target Species
Human
Target Name
HAL
Target Full Name
Histidine ammonia-lyase
Target Involvement
Histidinemia (HISTID)
Target Protein Families
PAL/histidase family
Target Synonyms
IS; hutH 1; Hal; HAL protein; Histidase; Histidine ammonia lyase; Histidine ammonia-lyase; HSTD; HutH; HUTH_HUMAN
Target Background
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene.
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