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The antibody against HDGF was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human HDGF (P51858) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against HDGF was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human HDGF (P51858) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-14444A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HDGF |
| Target Synonyms | HMG1L2; HDGF | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A549, Hep G2, Mouse liver, Rat liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HDGF (P51858). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | YQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNST | Uniprot ID | P51858 |
Uniprot Id
P51858
Target Species
Human
Target Name
HDGF
Target Full Name
Hepatoma-derived growth factor
Target Function
Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein.; Does not have mitogenic activity for fibroblasts. Does not bind heparin.; Has mitogenic activity for fibroblasts. Heparin-binding protein.
Target Subcellular Location
[Isoform 1]: Nucleus. Cytoplasm. Secreted, extracellular exosome.; [Isoform 2]: Nucleus. Cytoplasm. Secreted, extracellular exosome.; [Isoform 3]: Nucleus. Cytoplasm. Secreted, extracellular exosome.
Target Protein Families
HDGF family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cancer
Target Synonyms
FLJ96580; HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2
Target Background
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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