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The antibody against HMG20A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against HMG20A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02591A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HMG20A |
| Target Synonyms | HMGX1; HMGXB1; HMG20A | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, 293F, Mouse brain | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human HMG20A (NP_060670.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NP66 | Immunogen Sequence |
Uniprot Id
Q9NP66
Target Species
Human
Target Name
HMG20A
Target Full Name
High mobility group protein 20A
Target Function
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
FLJ10739; High mobility group 20A; High mobility group protein 20A; HM20A_HUMAN; HMG box containing protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain protein HMGX1 ; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; hmg20a; HMGX1 ; HMGXB1; Hypothetical protein FLJ10739; iBRAF; Inhibitor of BRAF35
Target Background
Enables identical protein binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of neuron differentiation; negative regulation of protein sumoylation; and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
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