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Rabbit anti-Human HMG20A Polyclonal Antibody

The antibody against HMG20A was raised in rabbit using the Human HMG20A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-53121A

The antibody against HMG20A was raised in rabbit using the Human HMG20A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-53121A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHMG20A
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman HMG20ATarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NP66
Background Information
  • Uniprot Id

    Q9NP66

  • Target Species

    Human

  • Target Name

    HMG20A

  • Target Full Name

    High mobility group protein 20A

  • Target Function

    Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    FLJ10739; High mobility group 20A; High mobility group protein 20A; HM20A_HUMAN; HMG box containing protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain protein HMGX1 ; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; hmg20a; HMGX1 ; HMGXB1; Hypothetical protein FLJ10739; iBRAF; Inhibitor of BRAF35

  • Target Background

    Enables identical protein binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of neuron differentiation; negative regulation of protein sumoylation; and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.

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