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The antibody against HNRNPLL was raised in rabbit using the Synthesized peptide derived from the Internal region of Human hnRNP LL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against HNRNPLL was raised in rabbit using the Synthesized peptide derived from the Internal region of Human hnRNP LL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of COLO205 cells using hnRNP LL Polyclonal Antibody
| Cat.No | ADC-38470A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HNRNPLL |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human hnRNP LL. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WVV9 |
Uniprot Id
Q8WVV9
Target Species
Human
Target Name
HNRNPLL
Target Full Name
Heterogeneous nuclear ribonucleoprotein L-like
Target Function
RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
Target Tissue Specificity
Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.
Target Synonyms
BLOCK24; Heterogeneous nuclear ribonucleoprotein L like; Heterogeneous nuclear ribonucleoprotein L-like; HNRLL_HUMAN; hnRNPLL; HNRPLL; SRRF; Stromal RNA regulating factor ; Stromal RNA-regulating factor
Target Background
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).
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