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The antibody against HORMAD1 was raised in rabbit using the Recombinant Human HORMA domain-containing protein 1 protein (201-394AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HORMAD1 was raised in rabbit using the Recombinant Human HORMA domain-containing protein 1 protein (201-394AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-19344A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HORMAD1 |
| Target Synonyms | HORMAD1 antibody; NOHMA antibody; HORMA domain-containing protein 1 antibody; Cancer/testis antigen 46 antibody; CT46 antibody; Newborn ovary HORMA protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human HORMA domain-containing protein 1 protein (201-394AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86X24 |
Uniprot Id
Q86X24
Target Species
Human
Target Name
HORMAD1
Target Full Name
HORMA domain-containing protein 1
Target Function
Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Target Subcellular Location
Nucleus. Chromosome.
Target Tissue Specificity
Testis-specific. Over-expressed in carcinomas.
Target Synonyms
HORMAD1; NOHMA; HORMA domain-containing protein 1; Cancer/testis antigen 46; CT46; Newborn ovary HORMA protein
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