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Rabbit anti-Human HS3ST3B1 Polyclonal Antibody, Biotin conjugated

The antibody against HS3ST3B1 was raised in rabbit using the Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-55071A

The antibody against HS3ST3B1 was raised in rabbit using the Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-55071A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHS3ST3B1
Target Synonyms3OST3B1 HS3ST3B, Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B), HS3ST3B1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateBiotin conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y662
Background Information
  • Uniprot Id

    Q9Y662

  • Target Species

    Human

  • Target Name

    HS3ST3B1

  • Target Full Name

    Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

  • Target Function

    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Sulfotransferase 1 family

  • Target Tissue Specificity

    Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney.

  • Target Synonyms

    HS3ST3B1; 3OST3B1; HS3ST3BHeparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC 2.8.2.30; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; 3-OST-3B; Heparan sulfate 3-O-sulfotransferase 3B1; h3-OST-3B

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