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Rabbit anti-Human HSP20/HSPB6 Polyclonal Antibody

The antibody against HSP20/HSPB6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human HSP20/HSP20/HSPB6 (NP_653218.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05817A

The antibody against HSP20/HSPB6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human HSP20/HSP20/HSPB6 (NP_653218.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05817A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHSP20/HSPB6
Target SynonymsHEL55; Hsp20; PPP1R91; HSP20/HSPB6FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, A375, Rat skeletal muscleApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human HSP20/HSP20/HSPB6 (NP_653218.1).Target SpeciesHuman
Immunogen SequenceMEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYLRAPSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAKUniprot IDO14558
Background Information
  • Uniprot Id

    O14558

  • Target Species

    Human

  • Target Name

    HSPB6

  • Target Full Name

    Heat shock protein beta-6

  • Target Function

    Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Secreted.

  • Target Protein Families

    Small heat shock protein (HSP20) family

  • Target Synonyms

    epididymis luminal protein 55; FLJ32389; Heat shock 20 kDa like protein p20 ; Heat shock 20 kDa-like protein p20; Heat shock protein alpha crystallin related B6; Heat shock protein beta 6 ; Heat shock protein beta-6; Heat shock protein; 20-KD; Heat-shock 27-KD protein 6; HEL55; Hsp20; HspB6; HSPB6_HUMAN

  • Target Background

    This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation.

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