Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against HTATSF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HTATSF1 (NP_055315.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against HTATSF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HTATSF1 (NP_055315.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-05579A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HTATSF1 |
| Target Synonyms | TATSF1; TAT-SF1; dJ196E23.2; HTATSF1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, Jurkat | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HTATSF1 (NP_055315.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNL | Uniprot ID | O43719 |
Uniprot Id
O43719
Target Species
Human
Target Name
HTATSF1
Target Full Name
17S U2 SnRNP complex component HTATSF1
Target Function
Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.
Target Subcellular Location
Nucleus.
Target Protein Families
HTATSF1 family
Target Tissue Specificity
Widely expressed.
Target Synonyms
HTATSF1HIV Tat-specific factor 1; Tat-SF1
Target Background
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
