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Rabbit anti-Human ICAM2 Polyclonal Antibody

The antibody against ICAM2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04424A

The antibody against ICAM2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04424A ClonalityPolyclonal
Host SpeciesRabbitTarget NameICAM2
Target SynonymsCD102; ICAM2FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, JurkatApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 25-223 of human ICAM2 (NP_000864.2).Target SpeciesHuman
Immunogen SequenceKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQUniprot IDP13598
Background Information
  • Uniprot Id

    P13598

  • Target Species

    Human

  • Target Name

    ICAM2

  • Target Full Name

    Intercellular adhesion molecule 2

  • Target Function

    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein. Cell projection, microvillus.

  • Target Protein Families

    Immunoglobulin superfamily, ICAM family

  • Target Synonyms

    ICAM2; Intercellular adhesion molecule 2; ICAM-2; CD antigen CD102

  • Target Background

    The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.

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