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The antibody against ICAM5 was raised in rabbit using the Recombinant Human Intercellular adhesion molecule 5 protein (32-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ICAM5 was raised in rabbit using the Recombinant Human Intercellular adhesion molecule 5 protein (32-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-16304A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ICAM5 |
| Target Synonyms | ICAM5 antibody; TLCN antibody; TLNIntercellular adhesion molecule 5 antibody; ICAM-5 antibody; Telencephalin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Intercellular adhesion molecule 5 protein (32-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UMF0 |
Uniprot Id
Q9UMF0
Target Species
Human
Target Name
ICAM5
Target Full Name
Intercellular adhesion molecule 5
Target Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, ICAM family
Target Tissue Specificity
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Target Synonyms
ICAM5; TLCN; TLNIntercellular adhesion molecule 5; ICAM-5; Telencephalin
Target Background
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
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