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The antibody against IFNA2 was raised in rabbit using the Recombinant Human Interferon alpha-2 protein (24-188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against IFNA2 was raised in rabbit using the Recombinant Human Interferon alpha-2 protein (24-188AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human glioma using IFNA2 Antibody at dilution of 1:1002
| Cat.No | ADC-50545A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IFNA2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Interferon alpha-2 protein (24-188AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01563 |
Uniprot Id
P01563
Target Species
Human
Target Name
IFNA2
Target Full Name
Interferon alpha-2
Target Function
Produced by macrophages, IFN-alpha have antiviral activities.
Target Subcellular Location
Secreted.
Target Protein Families
Alpha/beta interferon family
Target Research Area
Cancer
Target Synonyms
Alpha 2a interferon ; IFN alpha 2b; IFN-alpha-2; IFNA; Ifna2; IFNA2_HUMAN; INFA2; Interferon alpha 2; Interferon alpha A; Interferon alpha-2; Interferon alpha-A; LeIF A; LeIFA
Target Background
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.
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