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The antibody against IFRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human IFRD1 (NP_001541.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against IFRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human IFRD1 (NP_001541.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03577A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IFRD1 |
| Target Synonyms | PC4; TIS7; IFRD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | SW480 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human IFRD1 (NP_001541.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O00458 | Immunogen Sequence |
Uniprot Id
O00458
Target Species
Human
Target Name
IFRD1
Target Full Name
Interferon-related developmental regulator 1
Target Function
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal.
Target Protein Families
IFRD family
Target Tissue Specificity
Expressed in a variety of tissues.
Target Synonyms
12 O tetradecanoylphorbol 13 acetate induced sequence 7; IFRD1; IFRD1_HUMAN; interferon related developmental regulator 1; Interferon-related developmental regulator 1; Nerve growth factor inducible protein PC4 ; Nerve growth factor-inducible protein PC4; PC4; Pheochromocytoma cell 4; TIS7; TPA induced sequence 7
Target Background
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.
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