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The antibody against IGFBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-250 of human IGFBP1 (NP_000587.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against IGFBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-250 of human IGFBP1 (NP_000587.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11732A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IGFBP1 |
| Target Synonyms | AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IGFBP1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 150-250 of human IGFBP1 (NP_000587.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | ILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPN | Uniprot ID | P08833 |
Uniprot Id
P08833
Target Species
Human
Target Name
IGFBP1
Target Full Name
Insulin-like growth factor-binding protein 1
Target Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Target Subcellular Location
Secreted.
Target Synonyms
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IGFBP1
Target Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients.
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